This brief review deals with the recent progress in the implimentation of thio-Claisen rearrangement in synthetic organic chemistry. Thio-Claisen rearrangement has been utilized for the synthesis of many heterocyclic moieties of biological significance. Stereoselectivity of the thio-Claisen rearrangement has also been discussed. This short report mainly covers the literature published during 2003 onwards.
Keywords: Thio-Claisen rearrangement, thermal Claisen-rearrangement, catalyzed-Claisen rearrangement, asymmetric rearrangement, sulfur heterocycles, regioselective synthesis, stereoselective synthesis, electrocyclization, [3, 3]-sigmatropic shift, cyclodextrin, dihydroflustramine C, sequential Claisen rearrangement, [Rh2((S)-tbsp)4].