Abstract
Microemulsions are clear, transparent, thermodynamically stable dispersions of oil and water, stabilised by an interfacial film of surfactant frequently in combination with a co-surfactant. Recently, there has been a considerable interest for the microemulsion formulation, for the delivery of hydrophilic as well as lipophilic drug as drug carriers because of its improved drug solubilisation capacity, long shelf life, easy of preparation and improvement of bioavailability. In this present review, we discuss about the various advantages of microemulsion in pharmaceuticals, along with its composition variables, physicochemical characterisation etc. The potential use of microemulsion for therapeutic application is also discussed.
Keywords: Microemulsion, surfactants, formulation, characterisation, bioavailability, sustained release, parenteral, pharmaceutical use
Current Drug Delivery
Title: Microemulsions: A Potential Drug Delivery System
Volume: 3 Issue: 2
Author(s): P. K. Ghosh and R. S.R. Murthy
Affiliation:
Keywords: Microemulsion, surfactants, formulation, characterisation, bioavailability, sustained release, parenteral, pharmaceutical use
Abstract: Microemulsions are clear, transparent, thermodynamically stable dispersions of oil and water, stabilised by an interfacial film of surfactant frequently in combination with a co-surfactant. Recently, there has been a considerable interest for the microemulsion formulation, for the delivery of hydrophilic as well as lipophilic drug as drug carriers because of its improved drug solubilisation capacity, long shelf life, easy of preparation and improvement of bioavailability. In this present review, we discuss about the various advantages of microemulsion in pharmaceuticals, along with its composition variables, physicochemical characterisation etc. The potential use of microemulsion for therapeutic application is also discussed.
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Cite this article as:
Ghosh K. P. and Murthy S.R. R., Microemulsions: A Potential Drug Delivery System, Current Drug Delivery 2006; 3 (2) . https://dx.doi.org/10.2174/156720106776359168
DOI https://dx.doi.org/10.2174/156720106776359168 |
Print ISSN 1567-2018 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5704 |
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