Brain Connectivity Studies in Schizophrenia: Unravelling the Effects of Antipsychotics

Title:Brain Connectivity Studies in Schizophrenia: Unravelling the Effects of Antipsychotics

Volume: 10 Issue: 3

Author(s): Ayna B. Nejad, Bjorn H. Ebdrup, Birte Y. Glenthoj and Hartwig R. Siebner

Affiliation:

Keywords: Antipsychotic drug treatment, brain connectivity, fMRI, schizophrenia

Abstract: Impaired brain connectivity is a hallmark of schizophrenia brain dysfunction. However, the effect of drug treatment and challenges on the dysconnectivity of functional networks in schizophrenia is an understudied area. In this review, we provide an overview of functional magnetic resonance imaging studies examining dysconnectivity in schizophrenia and discuss the few studies which have also attempted to probe connectivity changes with antipsychotic drug treatment. We conclude with a discussion of possible avenues for further investigation.

Cite this article as:

B. Nejad Ayna, H. Ebdrup Bjorn, Y. Glenthoj Birte and R. Siebner Hartwig, Brain Connectivity Studies in Schizophrenia: Unravelling the Effects of Antipsychotics, Current Neuropharmacology 2012; 10 (3) . https://dx.doi.org/10.2174/157015912803217305