Innovative Topical Formulations for Treatment of Dermatitis

Taner      Senyigit; Ipek      Ozcan; Ozgen      Ozer

Abstract

The treatment of dermatitis with conventional dosage forms (ointment, cream, lotion etc.) has many concerns due to side effects especially in long-term therapy. Recent studies focused on strategies to optimize the potency of formulation while minimizing side effects. Several attempts have been made to increase the safety of treatment, including special vehicles (nanoparticle, liposome, patch etc.), combined therapy and new synthesized agents. This review provides major innovations and advances of new approaches for dermatitis treatment based on the published articles and patent applications.

Keywords: Alternative therapies, colloidal drug carrier systems, corticosteroids, dermatitis, nanoparticles, skin delivery, topical formulations, liposomes, eczema, chronic inflammatory skin disease.