Opioid Alkaloids in Fire Poppies, Papaver Californicum

Title: Opioid Alkaloids in Fire Poppies, Papaver Californicum

Volume: 2 Issue: 1

Author(s): James David Adams, Shin-Yu Lee, Julie Eunwoo Kim, Jirair Petrosyan, Mona Shahgholi and Roger Clemens

Affiliation:

Keywords: P. Californicum, papaveraceae, fire poppy, alkaloid, 14-methylnormorphine, papaverine, Ignimorphinan, Ignipapaverine, opioids, sterol

Abstract: P. Californicum (Papaveraceae), fire poppy, is traditionally used against pain. The seed pods were found to contain glycosides of 14-methylnormorphine and papaverine. The major alkaloid, ignimorphinan C67H80O19N2, is a mixture of sterol glycoside dimers of 14-methylnormorphine and papaverine. The second most abundant alkaloid, ignipapaverine C44H55O10N, is a sterol glycoside of papaverine. A possible glycoside of 2-methoxy-7-hydroxy-6-Omethyl- 7,8-dihydronormorphine-14-carbinol was found. Other compounds found were myricetin, malvidin-3-Oglucuronide and kaempferol acetate.

Cite this article as:

David Adams James, Lee Shin-Yu, Eunwoo Kim Julie, Petrosyan Jirair, Shahgholi Mona and Clemens Roger, Opioid Alkaloids in Fire Poppies, Papaver Californicum, The Natural Products Journal 2012; 2(1) . https://dx.doi.org/10.2174/2210315511202010031