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Anti-Infective Agents

Editor-in-Chief

ISSN (Print): 2211-3525
ISSN (Online): 2211-3533

2D- and 3D-QSAR Studies of Flavonoids, Biflavones and Chalcones: Antiviral, Antibacterial, Antifungal, and Antimycobacterial Activities

Author(s): Andrew G. Mercader and Alicia B. Pomilio

Volume 10, Issue 1, 2012

Page: [41 - 54] Pages: 14

DOI: 10.2174/2211362611201010041

Price: $65

Abstract

Flavonoids comprise a group of naturally occurring compounds that are known by their biological properties. Antiviral, antibacterial, antifungal, and antimycobacterial activities were analyzed. The results were discussed in terms of the bioactivity tested, and the structure-activity relationship (SAR), bidimensional (2D)- and three-dimensional (3D)- quantitative structure-activity relationship (QSAR) studies carried out on flavones, flavanones, chalcones, and some biflavonoids.

Keywords: Antiviral, antibacterial, antifungal, antimycobacterial agents, biflavonoids, chalcones, 2D-QSAR, 3D-QSAR, flavones, flavanones


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