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Current Inorganic Chemistry (Discontinued)


ISSN (Print): 1877-9441
ISSN (Online): 1877-945X

Luminescent Lanthanide Labels

Author(s): Loic J. Charbonniere

Volume 1, Issue 1, 2011

Page: [2 - 16] Pages: 15

DOI: 10.2174/1877944111101010002


This chapter describes the properties of luminescent lanthanide complexes that can be used in biological solutions for luminescence based labelling applications. The particular photo-physical specifications of this family of luminescent labels will be described, followed by the chemical and physico-chemical requirements necessary to reach high luminescence and good labelling activity. Following these criteria, examples of the literature will be detailed, following a classification based on the chemically activated function used in the labelling process.

Keywords: Lanthanide labels, bioconjugation, spectroscopic properties, microscopy, europium, terbium, N-hydroxySuccinimide (NHS), fluoro-immunoassays, Electronic transitions

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