Animal Models for Microbicide Studies

Title: Animal Models for Microbicide Studies

Volume: 10 Issue: 1

Author(s): Ronald S. Veazey, Robin J Shattock, Per Johan Klasse and John P. Moore

Affiliation:

Keywords: HIV, animal models, HIV transmission, mucosal transmission, vagina, rectum, microbicide, culture, cells, therapy

Abstract: There have been encouraging recent successes in the development of safe and effective topical microbicides to prevent vaginal or rectal HIV-1 transmission, based on the use of anti-retroviral drugs. However, much work remains to be accomplished before a microbicide becomes a standard element of prevention science strategies. Animal models should continue to play an important role in pre-clinical testing, with emphasis on safety, pharmacokinetic and efficacy testing.

Cite this article as:

S. Veazey Ronald, J Shattock Robin, Johan Klasse Per and P. Moore John, Animal Models for Microbicide Studies, Current HIV Research 2012; 10 (1) . https://dx.doi.org/10.2174/157016212799304715