Generic placeholder image

Current Drug Discovery Technologies


ISSN (Print): 1570-1638
ISSN (Online): 1875-6220

Inorganic Nanoparticles for Enhanced Photodynamic Cancer Therapy

Author(s): Shih-Hsun Cheng and Leu-Wei Lo

Volume 8, Issue 3, 2011

Page: [269 - 276] Pages: 8

DOI: 10.2174/157016311796798982

Price: $65


Photodynamic therapy (PDT) in cancer treatment uses photosensitizers to generate singlet oxygen followed by photoirradiation. The efficacy of PDT is greatly determined by the dosimetry of activation light and the photosensitizer (PS), modulating the photodynamic reaction at depth in diseased tissue. Development of nano-formulated photosensitizer has emerged as a promising field because of the biocompatibility and the accessibility for multi-functionalization of nanoparticles. In this review, we summarize the contemporary progress in use of inorganic nanoparticles for improvement of PDT in cancer therapeutics.

Keywords: Photodynamic therapy (PDT), photosensitizer (PS), nanodelivery, hydrophobic, Silica nanoparticles, Superparamagnetic iron oxide, Quantum dots, photothermal therapy, Multifunctional nanoparticles, hyperthermia

Rights & Permissions Print Export Cite as
© 2023 Bentham Science Publishers | Privacy Policy