Abstract
This review gives a survey on the use and applications of technetium-94m (94mTc) as a non-conventional positron emission tomography (PET) radionuclide for molecular imaging. The first part of this review describes the production and processing of 94mTc. The second part covers basic concepts of technetium coordination chemistry with a special focus on the synthesis of 94mTc-labeled compounds for molecular imaging purposes. The review concludes with a summary and an outlook on the prospects of using 94mTc in the field of PET chemistry and molecular imaging.
Keywords: Technetium-94m, positron emission tomography, radiopharmaceuticals, molecular imaging, 94mTc Production, Thermochromatographic Separation, Solvent Extraction, PET Imaging, COORDINATION CHEMISTRY
Current Radiopharmaceuticals
Title: Radiotracers Based on Technetium-94m
Volume: 4 Issue: 2
Author(s): Katherine Gagnon, Steve McQuarrie, Doug Abrams, Alexander J. McEwan and Frank Wuest
Affiliation:
Keywords: Technetium-94m, positron emission tomography, radiopharmaceuticals, molecular imaging, 94mTc Production, Thermochromatographic Separation, Solvent Extraction, PET Imaging, COORDINATION CHEMISTRY
Abstract: This review gives a survey on the use and applications of technetium-94m (94mTc) as a non-conventional positron emission tomography (PET) radionuclide for molecular imaging. The first part of this review describes the production and processing of 94mTc. The second part covers basic concepts of technetium coordination chemistry with a special focus on the synthesis of 94mTc-labeled compounds for molecular imaging purposes. The review concludes with a summary and an outlook on the prospects of using 94mTc in the field of PET chemistry and molecular imaging.
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Cite this article as:
Gagnon Katherine, McQuarrie Steve, Abrams Doug, J. McEwan Alexander and Wuest Frank, Radiotracers Based on Technetium-94m, Current Radiopharmaceuticals 2011; 4 (2) . https://dx.doi.org/10.2174/1874471011104020090
DOI https://dx.doi.org/10.2174/1874471011104020090 |
Print ISSN 1874-4710 |
Publisher Name Bentham Science Publisher |
Online ISSN 1874-4729 |
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