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Current Drug Targets


ISSN (Print): 1389-4501
ISSN (Online): 1873-5592

The Cancer Related Thrombotic Tendency in Sepsis

Author(s): David E. Joyce

Volume 8, Issue 4, 2007

Page: [543 - 549] Pages: 7

DOI: 10.2174/138945007780362773

Price: $65


The host inflammatory response is activated in both cancer and infection. This includes enhanced production of acute phase reactants, involvement of coagulation and inflammation and the potential for systemic effects. This overview will identify the prothrombotic links between cancer and sepsis and suggest antithrombotic agents as an approach in the specific treatment of sepsis in cancer patients.

Keywords: Cancer, thrombosis, sepsis, severe sepsis, inflammation, anticoagulant, coagulation, adenocarcinoma

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