Abstract
Prevalence of obesity and bronchial asthma is increasing in industrialized countries. Several studies have suggested a relationship between these disorders. Evidence comes from studies with animal models as well as epidemiologic observations. Moreover, pulmonary function parameters, genetic and hormonal factors support the hypothesis that obesity and asthma are linked. Given the enormous economic impact effective and efficient treatment strategies for both diseases are important. The present review will describe patents and recent developments in drugs directed against obesity and asthma. Potential therapeutic targets include the ORL-1 receptor, the LPA receptor, the VEGF receptor, cannaboid receptor, T cells, and protein kinases.
Keywords: Asthma, cannaboid receptor, LPA receptor, obesity, ORL-1 receptor, protein kinase, T cell, VEGF receptor
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
Title: Obesity and Asthma
Volume: 3 Issue: 3
Author(s): Hans-Peter Hauber and Michael Wegmann
Affiliation:
Keywords: Asthma, cannaboid receptor, LPA receptor, obesity, ORL-1 receptor, protein kinase, T cell, VEGF receptor
Abstract: Prevalence of obesity and bronchial asthma is increasing in industrialized countries. Several studies have suggested a relationship between these disorders. Evidence comes from studies with animal models as well as epidemiologic observations. Moreover, pulmonary function parameters, genetic and hormonal factors support the hypothesis that obesity and asthma are linked. Given the enormous economic impact effective and efficient treatment strategies for both diseases are important. The present review will describe patents and recent developments in drugs directed against obesity and asthma. Potential therapeutic targets include the ORL-1 receptor, the LPA receptor, the VEGF receptor, cannaboid receptor, T cells, and protein kinases.
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Cite this article as:
Hauber Hans-Peter and Wegmann Michael, Obesity and Asthma, Recent Patents on Endocrine, Metabolic & Immune Drug Discovery 2009; 3 (3) . https://dx.doi.org/10.2174/187221409789104773
DOI https://dx.doi.org/10.2174/187221409789104773 |
Print ISSN 1872-2148 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3334 |
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