Acceptance Tests and Quality Control of Ge/ Ga Generators

Title: Acceptance Tests and Quality Control of Ge/ Ga Generators

Volume: 2 Issue: 3

Author(s): Gianfranco Cicoria, Mario Marengo, Davide Pancaldi, Donato Di Pierro, Anna Rizzello, Filippo Lodi, Stefano Fanti and Stefano Boschi

Affiliation:

Keywords: Ga/, Ge generator, radionuclidic purity, quality assurance

Abstract: In this paper we describe test methods useful to evaluate the performance of Ge/ Ga generators and to assess radionuclidic purity of the eluates. In our tests on the elution profile of the generator, we found that less than 8.0 ml are sufficient to recover > 98 % of the activity. Elution yield was conforming the manufacturer specifications, being initially > 85 % and still > 64 % after 7 months of use. 68Ge breakthrough in the eluates was limited; even if radionuclidic purity was > 99.99 % , further analyses, in addition to physical tests, is recommended in order to assess chemical impurities that could determine interferences in labelling procedures.

Cite this article as:

Cicoria Gianfranco, Marengo Mario, Pancaldi Davide, Di Pierro Donato, Rizzello Anna, Lodi Filippo, Fanti Stefano and Boschi Stefano, Acceptance Tests and Quality Control of Ge/ Ga Generators, Current Radiopharmaceuticals 2009; 2(3) . https://dx.doi.org/10.2174/1874471010902030165