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Current Radiopharmaceuticals


ISSN (Print): 1874-4710
ISSN (Online): 1874-4729

Acceptance Tests and Quality Control of Ge/ Ga Generators

Author(s): Gianfranco Cicoria, Mario Marengo, Davide Pancaldi, Donato Di Pierro, Anna Rizzello, Filippo Lodi, Stefano Fanti and Stefano Boschi

Volume 2, Issue 3, 2009

Page: [165 - 168] Pages: 4

DOI: 10.2174/1874471010902030165

Price: $65


In this paper we describe test methods useful to evaluate the performance of Ge/ Ga generators and to assess radionuclidic purity of the eluates. In our tests on the elution profile of the generator, we found that less than 8.0 ml are sufficient to recover > 98 % of the activity. Elution yield was conforming the manufacturer specifications, being initially > 85 % and still > 64 % after 7 months of use. 68Ge breakthrough in the eluates was limited; even if radionuclidic purity was > 99.99 % , further analyses, in addition to physical tests, is recommended in order to assess chemical impurities that could determine interferences in labelling procedures.

Keywords: Ga/, Ge generator, radionuclidic purity, quality assurance

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