Abstract
Stroke stimulates neurogenesis in select regions of the adult brain, and the newborn neurons that result can migrate to areas of ischemic injury, where they may have the capacity to enhance brain recovery. These observations suggest that stroke-induced neurogenesis may contribute to endogenous brain repair after stroke, and that the mechanisms that underlie neurogenesis may represent potential therapeutic targets. Alternatively, transplantation of exogenously derived neural cells might also be an approach to the treatment of stroke.
Keywords: Stroke, ischemia, neurogenesis, proliferation, migration, differentiation
CNS & Neurological Disorders - Drug Targets
Title: Neurogenesis and Stroke
Volume: 6 Issue: 5
Author(s): David A. Greenberg
Affiliation:
Keywords: Stroke, ischemia, neurogenesis, proliferation, migration, differentiation
Abstract: Stroke stimulates neurogenesis in select regions of the adult brain, and the newborn neurons that result can migrate to areas of ischemic injury, where they may have the capacity to enhance brain recovery. These observations suggest that stroke-induced neurogenesis may contribute to endogenous brain repair after stroke, and that the mechanisms that underlie neurogenesis may represent potential therapeutic targets. Alternatively, transplantation of exogenously derived neural cells might also be an approach to the treatment of stroke.
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Cite this article as:
Greenberg A. David, Neurogenesis and Stroke, CNS & Neurological Disorders - Drug Targets 2007; 6 (5) . https://dx.doi.org/10.2174/187152707783220901
DOI https://dx.doi.org/10.2174/187152707783220901 |
Print ISSN 1871-5273 |
Publisher Name Bentham Science Publisher |
Online ISSN 1996-3181 |
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