Mechanisms Used by Human Papillomaviruses to Escape the Host Immune Response

Title: Mechanisms Used by Human Papillomaviruses to Escape the Host Immune Response

Volume: 7 Issue: 1

Author(s): Shreya Kanodia, Laura M. Fahey and W. Martin Kast

Affiliation:

Keywords: Papilloma virus, tumor immunology, immunotherapy, cancer

Abstract: The greatest risk factor for the development of cervical and other cancers that have been linked to the human papillomavirus (HPV) family is the persistence of the virus. To persist for the decades required to develop HPV-related cancers, the virus must escape host immunity. HPV is a simple DNA virus that has evolved to escape immune attack by a combination of stealth and interference. This review focuses on the mechanisms by which HPV can evade recognition by the host immune system.

Cite this article as:

Kanodia Shreya, Fahey M. Laura and Kast W. Martin, Mechanisms Used by Human Papillomaviruses to Escape the Host Immune Response, Current Cancer Drug Targets 2007; 7(1) . https://dx.doi.org/10.2174/156800907780006869