Generic placeholder image

Current Drug Targets - CNS & Neurological Disorders


ISSN (Print): 1568-007X
ISSN (Online): 1568-007X

Gastrointestinal Disturbances in Anorexia Nervosa and Bulimia Nervosa

Author(s): Sallie Jo Hadley and B. Timothy Walsh

Volume 2, Issue 1, 2003

Page: [1 - 9] Pages: 9

DOI: 10.2174/1568007033338715

Price: $65


Disturbances in the functioning of the upper gastrointestinal (GI ) tract have been described in both Anorexia Nervosa (AN) and Bulimia Nervosa (BN). Patients with AN experience substantial delays in gastric emptying as well as constipation. These problems may give rise to significant medical complications and may contribute to increased difficulties with refeeding and weight restoration. Reported GI disturbances in BN include increased gastric capacity, diminished gastric relaxation, delayed gastric emptying, diminished release of cholecystokinin (CCK) and abnormalities of enteric autonomic function, all of which may play a role in perpetuation of the syndrome. This article reviews evidence for the most common disturbances of GI function in AN and BN and discusses potential GI targets for therapeutic intervention.

Keywords: gastric emptying, gastric capacity, gastric relaxation, cck, autonomic dysfunction, anorexia nervosa, bulimia nervosa

Next »

Rights & Permissions Print Export Cite as
© 2023 Bentham Science Publishers | Privacy Policy