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Medicinal Chemistry Reviews - Online (Discontinued)

Editor-in-Chief

ISSN (Print): 1567-2034
ISSN (Online): 1567-2034

Hydroxamic Acids as Pharmacological Agents: An Update

Author(s): E. M.F. Muri, M. J. Nieto and J. S. Williamson

Volume 1, Issue 4, 2004

Page: [385 - 394] Pages: 10

DOI: 10.2174/1567203043401572

Price: $65

Abstract

The hydroxamic acid moiety plays an important role as a pharmacophore in a variety of biologically active agents. Such agents include enzyme inhibitors, anticancer agents, antimicrobial compounds, and agents used in the treatment of cardiovascular diseases, to name but a few. The following is an updated review of the basic medicinal chemistry and pharmacology of hydroxamic acids derivatives.

Keywords: Hydroxamic, antimicrobial, cardiovascular


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