Abstract
Ribozymes and small interfering RNAs (siRNAs) as well as non-natural RNA molecules, such as aptamers, can be used for detection and modulation of gene function at RNA and protein levels. These technologies provide overlapping and complementary methods to antibody-based protein detection. Functional RNAs offer easy to design and simple tools for understanding the function of genes and their products and have potential as therapeutic agents. We review here the advances made with functional RNAs, and illustrate their promise as tools for both in vitro and in vivo proteomic studies.
Keywords: rna, proteomics
Current Proteomics
Title: Functional RNAs as Tools in Proteomics
Volume: 2 Issue: 2
Author(s): N. K. Vaish and S. Zinnen
Affiliation:
Keywords: rna, proteomics
Abstract: Ribozymes and small interfering RNAs (siRNAs) as well as non-natural RNA molecules, such as aptamers, can be used for detection and modulation of gene function at RNA and protein levels. These technologies provide overlapping and complementary methods to antibody-based protein detection. Functional RNAs offer easy to design and simple tools for understanding the function of genes and their products and have potential as therapeutic agents. We review here the advances made with functional RNAs, and illustrate their promise as tools for both in vitro and in vivo proteomic studies.
Export Options
About this article
Cite this article as:
Vaish K. N. and Zinnen S., Functional RNAs as Tools in Proteomics, Current Proteomics 2005; 2 (2) . https://dx.doi.org/10.2174/1570164054494190
DOI https://dx.doi.org/10.2174/1570164054494190 |
Print ISSN 1570-1646 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6247 |
Call for Papers in Thematic Issues
Mass spectrometry data acquisition and analysis for proteomics
The Thematic Issue on "Mass spectrometry data acquisition and analysis for proteomics" aims to explore the latest advancements and challenges in the field of proteomics through the lens of mass spectrometry. Proteomics, the large-scale study of proteins and their functions, plays a crucial role in understanding various biological processes and ...read more
Peptides: State-of-Art and Commercialisation Hurdles
The Editors of the Current Proteomics (CP) journal are highly privileged to welcome scientists to submit their scientific research and review articles to be considered for publication in the upcoming thematic issue. The topics should cover various aspects of peptides in regard to their synthetic methodologies, formulation approaches, pharmacological challenges, ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Recent Advances in the Synthesis of Sphingosine and Phytosphingosine, Molecules of Biological Significance
Current Organic Chemistry Vascular Dementia: Atherosclerosis, Cognition and Alzheimers Disease
Current Alzheimer Research Stereoselective Pharmacodynamics and Pharmacokinetics of Proton Pump Inhibitors
Current Drug Metabolism Experimental Research on Nitric Oxide and the Therapy of Alzheimer Disease: A Challenging Bridge
CNS & Neurological Disorders - Drug Targets Current Concepts in the Management of Diabetic Polyneuropathy
Current Diabetes Reviews Serum Interleukin-33 as a Biomarker in Predicting Neonatal Sepsis in Premature Infants
Combinatorial Chemistry & High Throughput Screening Overcoming the Hurdles of Tumor Immunity by Targeting Regulatory Pathways in Innate and Adaptive Immune Cells
Current Pharmaceutical Design Recent Advances in the Development of Antidepressants Targeting the Purinergic P2X7 Receptor
Current Medicinal Chemistry Editorial [Hot Topic: New Prospects for Treatment of Autoimmune Diseases (Executive Guest Editor: Alessandra Fierabracci)]
Current Pharmaceutical Design Evaluation of the Anti-Inflammatory Activities of Diclofenac Sodium, Prednisolone and Atorvastatin in Combination with Ascorbic Acid
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Current Evidence on the Evaluation and Management of Fever Without a Source in Infants Aged 0-90 Days: A Review
Reviews on Recent Clinical Trials Novel Oral Suspensions: A Review
Current Drug Delivery Allosteric Drugs and Seven Transmembrane Receptors
Current Topics in Medicinal Chemistry The Effects of Italian Mediterranean Organic Diet (IMOD) on Health Status
Current Pharmaceutical Design A Review on Rheumatoid Arthritis Interventions and Current Developments
Current Drug Targets Paraneoplastic Pemphigus: Autoimmune-Cancer Nexus in the Skin
Anti-Cancer Agents in Medicinal Chemistry Fighting Against Leishmaniasis: Search of Alkaloids as Future True Potential Anti-Leishmanial Agents
Mini-Reviews in Medicinal Chemistry Medicinal Plants and Bioactive Compounds for Diabetes Management: Important Advances in Drug Discovery
Current Pharmaceutical Design Human Model Neurons in Studies of Brain Cell Damage and Neural Repair
Current Molecular Medicine The Controversial Role of Adenosine A2A Receptor Antagonists as Neuro-protective Agents
Current Medicinal Chemistry - Central Nervous System Agents