Abstract
I describe a case of tachyphylaxis to pramipexole and its management in a patient with bipolar I disorder.
Keywords: Bipolar, Bipolar depression, Drug holiday, Loss of response, Pramipexole, Tachyphylaxis, Tolerance, caramazepine, lamotrigine, modafinil, quetiapine, Parkinson's disease, valproic acid, depression, antidepressants
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