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Current Organic Synthesis

Editor-in-Chief

ISSN (Print): 1570-1794
ISSN (Online): 1875-6271

Near-Infrared Dyes: Probe Development and Applications in Optical Molecular Imaging

Author(s): Donald D. Nolting, John C. Gore and Wellington Pham

Volume 8 , Issue 4 , 2011

Page: [521 - 534] Pages: 14

DOI: 10.2174/157017911796117223

Price: $65

Abstract

The recent emergence of optical imaging has brought forth a unique challenge for chemists: development of new biocompatible dyes that fluoresce in the near-infrared (NIR) region for optimal use in biomedical applications. This review describes the synthesis of NIR dyes and the design of probes capable of noninvasively imaging molecular events in small animal models.

Keywords: Cyanine, fluorescence, FRET, imaging, optical, probe, rhodamine, near-infrared (NIR) region, near-infrared (NIR) dyes, Fluorescent Dyes, Cyanine Dyes


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