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Current Organic Synthesis


ISSN (Print): 1570-1794
ISSN (Online): 1875-6271

Chiral Lewis Acid Catalysis in Water

Author(s): Chikako Ogawa and Shu Kobayashi

Volume 8, Issue 3, 2011

Page: [345 - 355] Pages: 11

DOI: 10.2174/157017911795529119

Price: $65


The progress of development in chiral Lewis acid catalyzed reaction in water is described. Lewis acid surfactant-combined catalyst and chiral bipyridine ligand complex realized catalytic asymmetric hydroxymethylation and ring-opening reaction in water successfully. Furthermore, silica-supported Lewis acid catalyst was applied for asymmetric hydroxylation in water.

Keywords: Aldol reaction, Chiral Lewis acid, Epoxide, Green chemistry, Lewis acid, Mannich reaction, Water, asymmetric, organic, solvents

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