Abstract
(γ-L-Glutamyl)putrescine and N1- and N8-(γ-L-glutamyl)spermidines, possible regioisomeric products of the polyamine glutamyl transferase of bacteria such as Escherichia coli and Pseudomonas aeruginosa, were synthesized from N-Boc-protected putrescine and 1,3-propanediamine.
Keywords: glutamylspermidine, glutamylputrescine, Pseudomonas aeruginosa, polyamine biosynthesis, polyamine glutamyl transferase
Letters in Organic Chemistry
Title: Synthesis of N1- and N8-(γ -L-Glutamyl)spermidines and (γ -L-Glutamyl) putrescine
Volume: 8 Issue: 1
Author(s): Kazuya Toho, Naoki Abe, Teiko Yamada, Yoshifumi Ito, Hiroyuki Konno, Shigefumi Kuwahara and Hiromasa Kiyota
Affiliation:
Keywords: glutamylspermidine, glutamylputrescine, Pseudomonas aeruginosa, polyamine biosynthesis, polyamine glutamyl transferase
Abstract: (γ-L-Glutamyl)putrescine and N1- and N8-(γ-L-glutamyl)spermidines, possible regioisomeric products of the polyamine glutamyl transferase of bacteria such as Escherichia coli and Pseudomonas aeruginosa, were synthesized from N-Boc-protected putrescine and 1,3-propanediamine.
Export Options
About this article
Cite this article as:
Toho Kazuya, Abe Naoki, Yamada Teiko, Ito Yoshifumi, Konno Hiroyuki, Kuwahara Shigefumi and Kiyota Hiromasa, Synthesis of N1- and N8-(γ -L-Glutamyl)spermidines and (γ -L-Glutamyl) putrescine, Letters in Organic Chemistry 2011; 8 (1) . https://dx.doi.org/10.2174/157017811794557813
DOI https://dx.doi.org/10.2174/157017811794557813 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
“Medical Clearance” of Psychiatric Patients in the Emergency Department
Adolescent Psychiatry Internet Addiction: A Systematic Review of Epidemiological Research for the Last Decade
Current Pharmaceutical Design Editorial [Hot Topic:Positron Emission Tomography (PET) in Medicinal Chemistry and Drug Discovery (Guest Editor: Ming-Rong Zhang)]
Current Topics in Medicinal Chemistry Diagnostic Boundaries of Autism Disorder Vs Pervasive Developmental Disorder Nos Comparative Observational Study and Literature Review
Current Clinical Pharmacology Identification of New Drug Targets and Biomarkers Related to Obesity and Eating Disorders: an Approach Based on Reward Deficit and Addiction
Current Pharmaceutical Design Nitric Oxide in Migraine
CNS & Neurological Disorders - Drug Targets In Vitro and In Vivo Transformations of Lutein
Mini-Reviews in Organic Chemistry Acute and Chronic Treatments with Quetiapine Increase Mitochondrial Respiratory Chain Complex Activity in the Rat Brain
Current Neurovascular Research Immunological Approaches to Prevent Neuronal Apoptosis During Neuroinflammation
Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents Dangerous Liaisons between Beta-Amyloid and Cholinergic Neurotransmission
Current Pharmaceutical Design Diagnosis and Possible Use of Traditional Medicinal Plant to combat COVID-19
Coronaviruses A Conventional and 2DCOS Infrared Approach to the Kinetics of Protein Misfolding
Current Protein & Peptide Science The Role of Mitochondrial Function in Glutamate-Dependent Metabolism in Neuronal Cells
Current Pharmaceutical Design Integrin α4β7 Antagonists: Activities, Mechanisms of Action and Therapeutic Prospects
Current Immunology Reviews (Discontinued) Systems Biology Approaches to a Rational Drug Discovery Paradigm
Current Topics in Medicinal Chemistry Disulfiram: An Old Therapeutic with New Applications
CNS & Neurological Disorders - Drug Targets Inflammatory Mediators in Smoke Inhalation Injury
Inflammation & Allergy - Drug Targets (Discontinued) Autoantibodies and Sjogren’s Syndrome: A Physiologist’s Perspective
Current Pharmaceutical Biotechnology Fruitless Wolfberry-Sprout Extract Rescued Cognitive Deficits and Attenuated Neuropathology in Alzheimer’s Disease Transgenic Mice
Current Alzheimer Research Screening for Inhibitors of Microglia to Reduce Neuroinflammation
CNS & Neurological Disorders - Drug Targets