Abstract
Late in utero exposure to antidepressants has been suspected of compromising neonatal adaptation.
Objectives: To analyze published information on the risk of neonatal withdrawal phenomena associated with antidepressant use during late pregnancy.
Methods: Computerized searches on MEDLINE, PsycINFO, ENBASE, and Cochrane Library (up to October 2010) were performed for selecting literature information published in English and investigating the safety of antidepressants when used during late pregnancy (50 articles).
Results: Antidepressant treatment during late pregnancy may significantly increase the rate of neonatal discontinuation symptoms of various degree of severity.
Conclusions: Further, prospective, large cohort studies are needed to clarify whether such symptoms can be prevented by suspending antidepressant treatment within the final month before parturition.
Keywords: Pregnancy, antidepressants, perinatal complications, behavioral teratogenicity, TCAs
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RARE CASES IN GYNECOLOGY-OBSTETRICS
With the development of diagnostic and therapeutic techniques (such as ART techniques) and the immersion of new pathologies (such as COVID19), we are witnessing an increase in the incidence of pathologies that were previously described as rare or exceptional. the practitioner sometimes confronts difficult situations in these cases in diagnostic ...read more
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