Abstract
This review discusses the most active natural and synthetic curarelike compounds demonstrating myorelaxants activity. The data are grouped according to chemical structures, namely, quinoline and isoquinoline myorelaxants, myorelaxants with saturated heterocyclic or alkylamine fragments, myorelaxants with a steroid framework, natural and synthetic alkaloid myorelaxants.
Keywords: Curarelike compounds, natural and synthetic myorelaxants, nondepolarizing and depolarizing substances, diquarternized myorelaxants, diquar-ternized myorelaxants, Strychnos, Chondodendron, curare alkaloids, relax-ant action, linkers, antitumor, anti-HIV, antimalarial, hypotensive, nondepolarizing substances, depolarizing substances, Isoquinoline Myorelaxants, Tubocurarine, Chondodendron tomentosum, Me-nispermaceae, Atracurium, nerve blockers, succinyl choline, tetrahydroisoquinoline chlo-rofumarates, cis-dibenzoquinolizine chlorofu-marates, piperidine, morpholine, indolenine, alkaloid thesine, central cyclobutane ring, anatruxonium, Diplacin, Qualidyl, alkanedicar-bonyl fragment, antagonists of acetylcholine, depo-larizing myorelaxant dithylinum, Sux-amethonium, Imbretyl, Paramyon, diadonium, decadonium, oligodimethylsi-loxanes
Mini-Reviews in Medicinal Chemistry
Title: Diquaternized Curarelike Myorelaxants: Structure and Biological Activity
Volume: 10 Issue: 13
Author(s): N. F. Salakhutdinov and G. A. Tolstikov
Affiliation:
Keywords: Curarelike compounds, natural and synthetic myorelaxants, nondepolarizing and depolarizing substances, diquarternized myorelaxants, diquar-ternized myorelaxants, Strychnos, Chondodendron, curare alkaloids, relax-ant action, linkers, antitumor, anti-HIV, antimalarial, hypotensive, nondepolarizing substances, depolarizing substances, Isoquinoline Myorelaxants, Tubocurarine, Chondodendron tomentosum, Me-nispermaceae, Atracurium, nerve blockers, succinyl choline, tetrahydroisoquinoline chlo-rofumarates, cis-dibenzoquinolizine chlorofu-marates, piperidine, morpholine, indolenine, alkaloid thesine, central cyclobutane ring, anatruxonium, Diplacin, Qualidyl, alkanedicar-bonyl fragment, antagonists of acetylcholine, depo-larizing myorelaxant dithylinum, Sux-amethonium, Imbretyl, Paramyon, diadonium, decadonium, oligodimethylsi-loxanes
Abstract: This review discusses the most active natural and synthetic curarelike compounds demonstrating myorelaxants activity. The data are grouped according to chemical structures, namely, quinoline and isoquinoline myorelaxants, myorelaxants with saturated heterocyclic or alkylamine fragments, myorelaxants with a steroid framework, natural and synthetic alkaloid myorelaxants.
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Cite this article as:
F. Salakhutdinov N. and A. Tolstikov G., Diquaternized Curarelike Myorelaxants: Structure and Biological Activity, Mini-Reviews in Medicinal Chemistry 2010; 10 (13) . https://dx.doi.org/10.2174/13895575110091248
DOI https://dx.doi.org/10.2174/13895575110091248 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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