Generic placeholder image

Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Spirobisnaphthalenes from Fungi and their Biological Activities

Author(s): L. Zhou, J. Zhao, T. Shan, X. Cai and Y. Peng

Volume 10, Issue 10, 2010

Page: [977 - 989] Pages: 13

DOI: 10.2174/138955710792007178

Price: $65


Spirobisnaphthalenes have a unique structural feature involving two or three oxygen atoms acting as bridges connecting two original naphthalene subunits. Most of these metabolites isolated from fungi exhibit significant antifungal, antibacterial and cytotoxic properties to show great potential applications in medicine and agriculture. This review focuses on their structural characters and biological activities, as well as their structure-activity relationship, mechanism of action, synthesis and biosynthesis.

Keywords: Spirobisnaphthalenes, spiroxin, preussomerin, deoxypreussomerin, fungi, biological activities

« Previous

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy