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Current Rheumatology Reviews


ISSN (Print): 1573-3971
ISSN (Online): 1875-6360

Systemic Sclerosis-Associated Interstitial Lung Disease: Lessons from Clinical Trials, Outcome Measures, and Future Study Design

Author(s): Dinesh Khanna, James R. Seibold, Athol Wells, Oliver Distler, Yannick Allanore, Chris Denton and Daniel E. Furst

Volume 6, Issue 2, 2010

Page: [138 - 144] Pages: 7

DOI: 10.2174/157339710791330768

Price: $65


Pulmonary involvement including interstitial lung disease (ILD) is the leading cause of mortality in patients with systemic sclerosis (scleroderma; SSc). This article reviews the current evidence based medicine regarding available therapies for SSc-ILD; discusses the lessons learned from recent SSc-ILD randomized controlled trials (RCTs); and proposes outcome measures and recommendations for design of future RCTs for SSc-ILD.

Keywords: Systemic sclerosis, lung, outcome measures

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