Abstract
Periodontal disease leads to destruction of the periodontium such as alveolar bone, cementum, the periodontal ligament, and gingiva. Effective treatment for periodontal tissue regeneration is important, because periodontal disease is related to several systemic diseases. However, various conventional therapies for periodontal tissue regeneration have shown limited and variable clinical outcomes. Thus, there are ongoing efforts to identify an alternative cell source, such as stem cells, for the development of new tissue engineering therapies. In this review, periodontal disease and the application of tissue engineering for periodontal tissue regeneration are discussed. In particular, adipose-derived stem cells are presented as an agent for restoring periodontal tissue defects.
Keywords: Adipose-derived stem cells, periodontal disease, periodontal tissue regeneration, tissue engineering, mesenchymal stem cells, fat tissue
Current Stem Cell Research & Therapy
Title: Periodontal Disease and Periodontal Tissue Regeneration
Volume: 5 Issue: 2
Author(s): Morikuni Tobita and Hiroshi Mizuno
Affiliation:
Keywords: Adipose-derived stem cells, periodontal disease, periodontal tissue regeneration, tissue engineering, mesenchymal stem cells, fat tissue
Abstract: Periodontal disease leads to destruction of the periodontium such as alveolar bone, cementum, the periodontal ligament, and gingiva. Effective treatment for periodontal tissue regeneration is important, because periodontal disease is related to several systemic diseases. However, various conventional therapies for periodontal tissue regeneration have shown limited and variable clinical outcomes. Thus, there are ongoing efforts to identify an alternative cell source, such as stem cells, for the development of new tissue engineering therapies. In this review, periodontal disease and the application of tissue engineering for periodontal tissue regeneration are discussed. In particular, adipose-derived stem cells are presented as an agent for restoring periodontal tissue defects.
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Cite this article as:
Tobita Morikuni and Mizuno Hiroshi, Periodontal Disease and Periodontal Tissue Regeneration, Current Stem Cell Research & Therapy 2010; 5 (2) . https://dx.doi.org/10.2174/157488810791268672
DOI https://dx.doi.org/10.2174/157488810791268672 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
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