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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Animal Bone Meal (ABM): A Novel Natural Catalyst for Thia-Michael Addition

Author(s): Yassine Riadi, Rachid Mamouni, Younes Abrouki, Mohammadine El Haddad, Nabil Saffaj, Said El Antri, Sylvain Routier, Gerald Guillaumet and Said Lazar

Volume 7, Issue 3, 2010

Page: [269 - 271] Pages: 3

DOI: 10.2174/157017810791112397

Price: $65


The preparation and use of Animal Bone Meal (ABM) as natural catalyst is described for C-S bond formation by thia-Michael addition. This new natural heterogeneous method led to β-sulfinyl adducts in very high yields after only a few minutes. Influence of the thiol derivatives and substitution on chalcones is discussed.

Keywords: Bones, animal bone meal, michael addition, chalcones, thiols, α,β-unsaturated ketones, X-Ray analysis

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