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Protein & Peptide Letters


ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Isolation and Partial Characterization of a Novel Lipid Transfer Protein (LTP) and Antifungal Activity of Peptides from Chilli Pepper Seeds

Author(s): Luana P. Cruz, Suzanna F.F. Ribeiro, Andre O. Carvalho, Ilka M. Vasconcelos, Rosana Rodrigues, Maura Da Cunha and Valdirene M. Gomes

Volume 17, Issue 3, 2010

Page: [311 - 318] Pages: 8

DOI: 10.2174/092986610790780305

Price: $65


The aims of this study were to isolate and characterize peptides present in chilli pepper seeds and evaluate their antifungal activities. An isolated peptide closer to 9 kDa showed high sequence homology to the antimicrobial peptide lipid transfer protein. The peptide fraction containing the LTP inhibited the growth of the fungi, Fusarium oxysporum, Colletotrium lindemunthianum, the yeasts, Saccharomyces cerevisiae, Pichia membranifaciens, Candida tropicalis, Candida albicans, inhibited glucose-stimulated acidification of the medium by yeast cells of S. cerevisiae and caused several morphological changes in P. membranifaciens.

Keywords: LTP, Capsicum annuum, plant antimicrobial peptides, yeast, filamentous fungi

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