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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

The Nitrile Functionality as a Directing Group in the Palladium-Catalysed Addition of Aryl Boronic Acids to Alkynes

Author(s): Arantxa Rodriguez and Wesley J. Moran

Volume 7, Issue 1, 2010

Page: [7 - 10] Pages: 4

DOI: 10.2174/157017810790533931

Price: $65


The nitrile group is shown to direct the palladium-catalysed hydroarylation of internal alkynes bearing a pendant nitrile with boronic acids.

Keywords: Palladium, catalysis, nitrile, directing-group, hydroarylation

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