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Infectious Disorders - Drug Targets


ISSN (Print): 1871-5265
ISSN (Online): 2212-3989

Q Fever Endocarditis

Author(s): Elias E. Mazokopakis, Christos M. Karefilakis and Ioannis K. Starakis

Volume 10, Issue 1, 2010

Page: [27 - 31] Pages: 5

DOI: 10.2174/187152610790410918

Price: $65


Coxiella burnetii, the agent of Q fever, produces a variety of clinical syndromes. The most frequent and serious chronic presentation is endocarditis, which presents unspecifically as a blood-culture negative endocarditis. It occurs almost exclusively in patients who have pre-existing valvular disease or who are immunocompromised. Without prompt recognition and appropriate antimicrobial therapy, the course of Q fever endocarditis is severe and potentially fatal. The epidemiology, signs and symptoms, laboratory findings, diagnosis and treatment of Q fever endocarditis are presented in our review.

Keywords: Endocarditis, Q fever

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