Can Statin be a Novel Pharmacophore for Antidiabetic Activity?

S.   A.   Parmar; A.   A.   Mehta

Abstract

Currently, statins are in lime light due to their pleiotropic effects. One of their pleiotropic effects is on glucose metabolism. Various clinical and preclinical studies were designed to evaluate statins effect on glucose metabolism. This review describes preclinical and clinical evidences of statins action on glucose metabolism.

Keywords: Statin, diabetes, insulin resistance, glucose metabolism, solubility