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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Can Statin be a Novel Pharmacophore for Antidiabetic Activity?

Author(s): S. A. Parmar and A. A. Mehta

Volume 9 , Issue 12 , 2009

Page: [1423 - 1428] Pages: 6

DOI: 10.2174/1389557789957340

Price: $65


Currently, statins are in lime light due to their pleiotropic effects. One of their pleiotropic effects is on glucose metabolism. Various clinical and preclinical studies were designed to evaluate statins effect on glucose metabolism. This review describes preclinical and clinical evidences of statins action on glucose metabolism.

Keywords: Statin, diabetes, insulin resistance, glucose metabolism, solubility

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