Abstract
We propose a sequence-based multiple classifier system, i.e., rotation forest, to infer protein-protein interactions (PPIs). Moreover, Moran autocorrelation descriptor is used to code an interaction protein pair. Experimental results on Saccharomyces cerevisiae and Helicobacter pylori datasets show that our approach outperforms those previously published in literature, which demonstrates the effectiveness of the proposed method.
Keywords: Protein-protein interactions, rotation forest, autocorrelation descriptor, protein sequence, multiple classifier system
Protein & Peptide Letters
Title: Sequence-Based Prediction of Protein-Protein Interactions by Means of Rotation Forest and Autocorrelation Descriptor
Volume: 17 Issue: 1
Author(s): Jun-Feng Xia, Kyungsook Han and De-Shuang Huang
Affiliation:
Keywords: Protein-protein interactions, rotation forest, autocorrelation descriptor, protein sequence, multiple classifier system
Abstract: We propose a sequence-based multiple classifier system, i.e., rotation forest, to infer protein-protein interactions (PPIs). Moreover, Moran autocorrelation descriptor is used to code an interaction protein pair. Experimental results on Saccharomyces cerevisiae and Helicobacter pylori datasets show that our approach outperforms those previously published in literature, which demonstrates the effectiveness of the proposed method.
Export Options
About this article
Cite this article as:
Xia Jun-Feng, Han Kyungsook and Huang De-Shuang, Sequence-Based Prediction of Protein-Protein Interactions by Means of Rotation Forest and Autocorrelation Descriptor, Protein & Peptide Letters 2010; 17 (1) . https://dx.doi.org/10.2174/092986610789909403
DOI https://dx.doi.org/10.2174/092986610789909403 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Application of Charge Transfer Reactions for the Quantitative Spectrophotometric Determination of Cyclophosphamide in Pure and Pharmaceutical Formulation
Current Pharmaceutical Analysis Metabolomics and the Diagnosis of Human Diseases -A Guide to the Markers and Pathophysiological Pathways Affected
Current Medicinal Chemistry Breast Cancer Resistance Protein: A Potential Therapeutic Target for Cancer
Current Drug Targets Rationale Design, Synthesis, Cytotoxicity Evaluation, and Molecular Docking Studies of 1,3,4-oxadiazole Analogues
Anti-Cancer Agents in Medicinal Chemistry Microbial Antigenic Pressure and Evolution of the Immune Response: Toward a Better Understanding of the Human Immune System in Health and Disease and Therapeutic Interventions
Endocrine, Metabolic & Immune Disorders - Drug Targets Current Evidence Regarding Low-carb Diets for The Metabolic Control of Type-2 Diabetes
Current Diabetes Reviews Probiotic Lactobacilli: A New Perspective for the Treatment of Inflammatory Bowel Disease
Current Pharmaceutical Design Pharmacological Evaluation of Polar Extract of <i>Chrozophora</i> tinctoria for Effective Treatment of Cancer: <i>In Vitro</i> Qualitative and Quantitative Analysis
Current Nutraceuticals Electrocatalytic Determination of 6-Mercaptopurine Using Multiwall Carbon Nanotubes Paste Electrode in the Presence of Methyldopa
Current Nanoscience Immunomodulators: Friends or Enemies in Surgery for Crohn’s Disease?
Current Drug Targets A Polylactosamine Specific Lectin from <i>Adenia hondala</i> Induces Apoptosis and Necrosis in Human Epithelial Colon Cancer HT-29 Cells
Protein & Peptide Letters Stability of Ketoprofen Methylester in Plasma of Different Species
Current Drug Metabolism Cyclopentenyl Cytosine (CPEC): An Overview of its in vitro and in vivo Activity
Current Cancer Drug Targets Retraction Notice: Protein Identification in Sub Proteome Fractions of Breast Cancer Cells by OFFGEL-IEF and iTRAQ Labeling
Current Proteomics Performance Analysis of Feature-Based Lung Tumor Detection and Classification
Current Medical Imaging Nucleosome Positioning Based on the Sequence Word Composition
Protein & Peptide Letters Synthesis and Evaluation of a Novel Gene Reporter Molecule: Detection of b-galactosidase Activity Using 19F NMR of a Fluorinated Vitamin B6 Conjugate+
Medicinal Chemistry Activity Based Probes for Proteases: Applications to Biomarker Discovery,Molecular Imaging and Drug Screening
Current Pharmaceutical Design Raman Spectroscopy and Imaging: Promising Optical Diagnostic Tools in Pediatrics
Current Medicinal Chemistry The Gold Nanorod-Biology Interface: From Proteins to Cells to Tissue
Current Physical Chemistry