Abstract
RipA is an important growth factor of M. tuberculosis. Its depletion produces decreasing bacterial growth and abnormal phenotype. RipA C-terminal fragment (263-472), containing its predicted catalytic domain has been successfully crystallized using vapor-diffusion methods. The structure has been solved by Multiwavelength Anomalous Dispersion and atomic resolution refinement is in progress.
Keywords: Resuscitation promoting factor, crystal, growth factor, x-ray, tuberculosis
Protein & Peptide Letters
Title: Expression, Purification, Crystallization and Preliminary X-Ray Crystallographic Analysis of the Resuscitation Promoting Factor Interacting Protein RipA from M. tuberculosis
Volume: 17 Issue: 1
Author(s): Alessia Ruggiero, Flavia Squeglia, Carla Esposito, Daniela Marasco, Emilia Pedone, Carlo Pedone and Rita Berisio
Affiliation:
Keywords: Resuscitation promoting factor, crystal, growth factor, x-ray, tuberculosis
Abstract: RipA is an important growth factor of M. tuberculosis. Its depletion produces decreasing bacterial growth and abnormal phenotype. RipA C-terminal fragment (263-472), containing its predicted catalytic domain has been successfully crystallized using vapor-diffusion methods. The structure has been solved by Multiwavelength Anomalous Dispersion and atomic resolution refinement is in progress.
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Cite this article as:
Ruggiero Alessia, Squeglia Flavia, Esposito Carla, Marasco Daniela, Pedone Emilia, Pedone Carlo and Berisio Rita, Expression, Purification, Crystallization and Preliminary X-Ray Crystallographic Analysis of the Resuscitation Promoting Factor Interacting Protein RipA from M. tuberculosis, Protein & Peptide Letters 2010; 17 (1) . https://dx.doi.org/10.2174/092986610789909557
DOI https://dx.doi.org/10.2174/092986610789909557 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
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