Diabetes and Antioxidants: Myth or Reality?

Title: Diabetes and Antioxidants: Myth or Reality?

Volume: 8 Issue: 5

Author(s): Mohamed A. Haidara, Hanaa Z. Yassin, Zorica Zakula, Dimitri P. Mikhailidis and Esma R. Isenovic

Affiliation:

Keywords: Diabetes, oxidative stress, antioxidants, statins

Abstract: Numerous studies have shown that increased oxidative stress (OxS) is present in diabetic patients. There is evidence that this OxS can be increased before complications associated with diabetes mellitus (DM) occur. However, the role and influence of OxS in the initiation and progression of DM remains the subject of debate. It has been suggested that in DM, OxS is caused by increased production of reactive oxygen species (ROS), and associated with reduction in antioxidant defenses and altered cellular redox status. Acute and chronic OxS which could enhance the development of complications associated with DM. This review considers recent findings on the role of antioxidants in controlling OxS and the incidence of DM with emphasis on animal and human studies.

Cite this article as:

A. Haidara Mohamed, Z. Yassin Hanaa, Zakula Zorica, P. Mikhailidis Dimitri and R. Isenovic Esma, Diabetes and Antioxidants: Myth or Reality?, Current Vascular Pharmacology 2010; 8 (5) . https://dx.doi.org/10.2174/157016110792006941