High Stereoselective Mannich Reaction Catalyzed by Starch Sulfonic Acid in Water

Title: High Stereoselective Mannich Reaction Catalyzed by Starch Sulfonic Acid in Water

Volume: 6 Issue: 6

Author(s): Yu Wan, Wei Lin, Xiu-Mei Chen, Yang Shen, Hai-Qiang Xin, Hua-Hong Xu, Rui Yuan, Li-Ling Pang, Rui Ma, Cai-Hui Yue, Wei Yin, Rong-Cheng Bo and Hui Wu

Affiliation:

Keywords: Highly stereoselective, Mannich reaction, Starch sulfonic acid

Abstract: Starch sulfonic acid was used as efficient and highly stereoselective catalyst for the three-component Mannich reaction of aldehydes, amines, and ketones in water at ambient temperature to afford the corresponding β-amino ketones in good to excellent stereoselectivity and yields.

Cite this article as:

Wan Yu, Lin Wei, Chen Xiu-Mei, Shen Yang, Xin Hai-Qiang, Xu Hua-Hong, Yuan Rui, Pang Li-Ling, Ma Rui, Yue Cai-Hui, Yin Wei, Bo Rong-Cheng and Wu Hui, High Stereoselective Mannich Reaction Catalyzed by Starch Sulfonic Acid in Water, Letters in Organic Chemistry 2009; 6 (6) . https://dx.doi.org/10.2174/157017809789124920