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Recent Patents on Anti-Cancer Drug Discovery


ISSN (Print): 1574-8928
ISSN (Online): 2212-3970

Use of the Semiconductor Nanotechnologies “Quantum Dots” for in vivo Cancer Imaging

Author(s): Monica Ciarlo, Patrizia Russo, Alfredo Cesario, Sara Ramella, Gabriella Baio, Carlo E. Neumaier and Laura Paleari

Volume 4, Issue 3, 2009

Page: [207 - 215] Pages: 9

DOI: 10.2174/157489209789206841

Price: $65


Non-invasive in vivo imaging offers great potential to facilitate translational drug development research at the animal testing phase. The emerging luminescent nanoparticles or quantum dots provide a new type of biological agents that can improve these applications. The advantages of luminescent nanoparticles for biological applications include their high quantum yield, color availability, good photo-stability, large surface-to-volume ratio, surface functionality, and small size. These properties could improve the sensitivity of biological detection and imaging by at least 10- to 100-fold and make them an exceptional tool for live-cell imaging. In this review patents on applications of semiconductor quantum dots for in vivo imaging are discussed.

Keywords: Quantum dots, in vivo imaging, cancer

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