Generic placeholder image

Current Alzheimer Research

Editor-in-Chief

ISSN (Print): 1567-2050
ISSN (Online): 1875-5828

Early Features in Frontotemporal Dementia

Author(s): Ana Maria Villamizar Caycedo, Bruce Miller, Joel Kramer and Katya Rascovsky

Volume 6, Issue 4, 2009

Page: [337 - 340] Pages: 4

DOI: 10.2174/156720509788929255

Price: $65

Abstract

Frontotemporal dementia is a disorder of paralimbic prefrontal-insular circuitry. The disorder is often sporadic but can be caused by genetic mutations in tau, progranulin, valosin, TDP-43 and CHMP2b. The major clinical manifestations of FTD include addictive behaviors, disinhibition, apathy, overeating and loss of sympathy and empathy for others. Treatment is currently focused around symptoms but disease-modifying therapies seem feasible.


Rights & Permissions Print Export Cite as
© 2022 Bentham Science Publishers | Privacy Policy