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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Medicinal Chemistry and Anti-Inflammatory Activity of Nitric Oxide-Releasing NSAI Drugs

Author(s): Esra Koc and S. Guniz Kucukguzel

Volume 9, Issue 5, 2009

Page: [611 - 619] Pages: 9

DOI: 10.2174/138955709788167556

Price: $65


Nitric Oxide, which acts as a non-specific cytotoxic mediator and a biological messenger on immunological competence, has been gaining significantly increasing importance. As an alternative to conventional NSAIDs having significant side effects, pharmacologically improved and therapeutically enhanced NO releasing non-steroidal antiinflammatory drugs with less side effects are being planned to produce.

Keywords: Nitric oxide, NO-NSAID, anti-inflammatory

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