Importance of a Potential Salt Bridge and Hydrophobic Core in the Function and Oligomerization of a Small Heat Shock Protein

Title: Importance of a Potential Salt Bridge and Hydrophobic Core in the Function and Oligomerization of a Small Heat Shock Protein

Volume: 17 Issue: 6

Author(s): Zhenzhen Wen, Yonghua Wang, Xun Xu, Bo Yang, Wencheng Li and Mingquan Xie

Affiliation:

Keywords: Small heat shock proteins (sHSPs), SsHSP14.1, Sulfolobus solfataricus (S. solfataricus), EcoR I, salt bridge, oligomer

Abstract: SsHSP14.1, a novel sHSP from the hyper-thermophilic archaeon Sulfolobus solfataricus (S. solfataricus), is reported herein to function to protect EcoR I from heat-induced inactivation. A predicted salt bridge and hydrophobic interactions were found to be important for this function.

Cite this article as:

Wen Zhenzhen, Wang Yonghua, Xu Xun, Yang Bo, Li Wencheng and Xie Mingquan, Importance of a Potential Salt Bridge and Hydrophobic Core in the Function and Oligomerization of a Small Heat Shock Protein, Protein & Peptide Letters 2010; 17(6) . https://dx.doi.org/10.2174/092986610791190273