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Protein & Peptide Letters


ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Importance of a Potential Salt Bridge and Hydrophobic Core in the Function and Oligomerization of a Small Heat Shock Protein

Author(s): Zhenzhen Wen, Yonghua Wang, Xun Xu, Bo Yang, Wencheng Li and Mingquan Xie

Volume 17, Issue 6, 2010

Page: [751 - 758] Pages: 8

DOI: 10.2174/092986610791190273

Price: $65


SsHSP14.1, a novel sHSP from the hyper-thermophilic archaeon Sulfolobus solfataricus (S. solfataricus), is reported herein to function to protect EcoR I from heat-induced inactivation. A predicted salt bridge and hydrophobic interactions were found to be important for this function.

Keywords: Small heat shock proteins (sHSPs), SsHSP14.1, Sulfolobus solfataricus (S. solfataricus), EcoR I, salt bridge, oligomer

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