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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Rapid Synthesis of Taxifolione and Taxifolial D, Two Metabolites from the Marine Alga Caulerpa taxifolia

Author(s): Fabien Fecourt, Cedric Carlier and Patrick Pale

Volume 6, Issue 1, 2009

Page: [65 - 70] Pages: 6

DOI: 10.2174/157017809787003179

Price: $65


The synthesis of two natural products - Taxifolione and Taxifolial D – isolated from the marine alga Caulerpa taxifolia invading the Mediterranean Sea was performed. Coupling reactions allowed for a rapid synthesis. The surprising Z configuration of Taxifolial D was confirmed after synthesis and comparison of each synthetic stereoisomer.

Keywords: Terpenoids, enynes, cross-coupling, antitumor agents

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