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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Lanthanide(III) Chelates for Selective Solution Phase Labeling of Biomolecules

Author(s): Janne Ketola, Lassi Jaakkola and Jari Hovinen

Volume 5, Issue 6, 2008

Page: [444 - 449] Pages: 6

DOI: 10.2174/157017808785740462

Price: $65


Synthesis of photoluminescent lanthanide(III) chelates that allow selective solution phase labeling of bioactive molecules using phosphate elimination, native chemical ligation, and ‘click-chemisty’ is described.

Keywords: Native chemical ligation, phosphate elimination, ‘click chemistry’, lanthanide(III) chelates, labeling

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