Generic placeholder image

Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

The Facile and Efficient Three-Component One-Pot Mannich-Type Reaction of Indoles Catalyzed by In(OTf)3 Under Microwave Irradiations

Author(s): Dipak Prajapati, Sunil Gadhwal and Rupam Sarma

Volume 5, Issue 5, 2008

Page: [365 - 369] Pages: 5

DOI: 10.2174/157017808784872133

Price: $65

Abstract

Indium triflate catalysed the three-component one-pot reaction of indole 1 with a heteroimine generated in situ under microwave irradiations and afforded predominately secondary indolyl amines 4 in excellent yields as well as bisindolyl methane 5 in poor yields. The catalyst indium triflate can be recovered after the reaction and reused in the subsequent experiments.

Keywords: Indoles, indium triflate, microwave irradiations, multicomponent reactions, Mannich-type reactions, bisindolyl methane


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy