QSAR Studies on some Calcium Channel Blockers

Title: QSAR Studies on some Calcium Channel Blockers

Volume: 5 Issue: 5

Author(s): Mallari A. Naik, V. S.A. Kumar Satuluri and S. P. Gupta

Affiliation:

Abstract: Quantitative structure-activity relationship studies have been made on some calcium channel blockers (CCBs) that include the most widely studied class of 1,4-dihydropyridines and two new classes of CCBs, namely benzazepinone analogs and quinolizidinyl derivatives. In the case of 1,4-dihydropyridines some simple correlations have been found as compared to those reported in several earlier studies and in the other two classes it could be shown that the electronic parameters and the bulk of the molecules may be important for the activity of the compounds.

Cite this article as:

Naik A. Mallari, Kumar Satuluri S.A. V. and Gupta P. S., QSAR Studies on some Calcium Channel Blockers, Letters in Drug Design & Discovery 2008; 5 (5) . https://dx.doi.org/10.2174/157018008784912090