Prediction of Binding Motifs in Hepatitis C Virus NS5A and Human Proteins

Title: Prediction of Binding Motifs in Hepatitis C Virus NS5A and Human Proteins

Volume: 15 Issue: 5

Author(s): Guang-Zheng Zhang and Kyungsook Han

Affiliation:

Keywords: Binding motif, protein-protein interaction, hepatitis C virus, human protein, binding site

Abstract: From the extensive analysis, we identified three highly conserved sequence segments in HCV NS5A proteins and one binding motif in human proteins. The binding motif of human proteins often forms a full helix or an extended strand-loop structure, and is in good agreement with the experimental findings of previous studies.

Cite this article as:

Zhang Guang-Zheng and Han Kyungsook, Prediction of Binding Motifs in Hepatitis C Virus NS5A and Human Proteins, Protein & Peptide Letters 2008; 15 (5) . https://dx.doi.org/10.2174/092986608784567500