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Protein & Peptide Letters


ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Protein Domain Annotation with Predicted Domain-Domain Interaction Networks

Author(s): Xing-Ming Zhao, Yong Wang, Luonan Chen and Kazuyuki Aihara

Volume 15 , Issue 5 , 2008

Page: [456 - 462] Pages: 7

DOI: 10.2174/092986608784567609

Price: $65


This paper presents a framework for annotating protein domains with predicted domain-domain interaction networks. Specially, domain annotation is formalized as a multi-class classification problem in this work. The numerical experiments on InterPro domains show promising results, which proves the efficiency of our proposed methods.

Keywords: Predicted domain-domain interaction, domain annotation, majority rule, diffusion kernel, shortest path

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