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Letters in Drug Design & Discovery


ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

A Novel Strategy to Manage Tolerance to Lamotrigine in Bipolar II Depression

Author(s): V. Sharma and C. Corpse

Volume 5, Issue 4, 2008

Page: [302 - 302] Pages: 1

DOI: 10.2174/157018008784619924

Price: $65


We describe the case of a patient with refractory bipolar II depression who developed tolerance to lamotrigine and after failing to respond to dose escalation showed a robust response to a retrial of lamotrigine following a two week drug holiday.

Keywords: Lamotrigine, Bipolar II depression, Bipolar II disorder, Tolerance, Drug holiday, Retrial

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