Generic placeholder image

Letters in Drug Design & Discovery


ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Modulation by Dopaminergic System of Morphine Withdrawal: In Vitro Evidences

Author(s): A. Capasso

Volume 5, Issue 4, 2008

Page: [297 - 301] Pages: 5

DOI: 10.2174/157018008784619906

Price: $65


The effects exerted by cocaine, amphetamine and phencyclidine on the acute opiate withdrawal induced by morphine were investigated in vitro. The results of our experiments indicate that cocaine, amphetamine and phencyclidine are able to influence opiate withdrawal in vitro thus confirming an important functional interaction between the dopaminergic system and opioid withdrawal.

Keywords: Dependence, Dopamine, Morphine, Cocaine, Amphetamine, Phencyclidine

Rights & Permissions Print Export Cite as
© 2023 Bentham Science Publishers | Privacy Policy