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Current Topics in Medicinal Chemistry


ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

New Agents to Treat Life-Threatening Fungal Infections

Author(s): Pauline C. Ting and Scott S. Walker

Volume 8, Issue 7, 2008

Page: [592 - 602] Pages: 11

DOI: 10.2174/156802608783955610

Price: $65


Fungi can cause life threatening diseases, particularly in patients with weakened immune systems. While treatment options are available for these individuals, dose limiting toxicity and the appearance of drug resistant organisms are growing problems. Therefore, the identification, development, and registration of new, safe, and efficacious agents are needed. Herein, we review recent developments in the field of antifungal drug discovery. We focus on recently launched drugs (triazoles and echinocandins), agents in clinical development, and compounds in discovery.

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