Generic placeholder image

Letters in Drug Design & Discovery


ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Propofol and Systemic Inflammatory Response in Abdominal Aortic Surgery

Author(s): Jose M. Rodriguez-Lopez and Francisco S. Lozano

Volume 5, Issue 2, 2008

Page: [148 - 151] Pages: 4

DOI: 10.2174/157018008783928490

Price: $65


Abdominal aortic surgery is relatively common associated with considerable postoperative morbidity and mortality. The aortic cross-clamping for the implantation of a vascular prosthetic graft induces a systemic inflammatory response (SIR) because of an ischemia-reperfusion (IR) injury. In our experimental models we have reported that propofol anesthesia, compared with sevoflurane, after IR modulates SIR and this effect might result in renal protection.

Keywords: Propofol, Systemic inflammatory response, Aortic surgery, Aortic cross-clamping

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy